







Xếp hạng theo doanh thu phòng vé Việt Nam (Box Office Vietnam).
| 2026 | Tội Phạm 101 | Angie |
| 2025 | Màn đêm luôn tới | Doreen |
| 2024 | Poolman | Susan Kerkovish |
| 2022 | Sharp Stick | Marilyn |
| 2021 | Thức Giấc | Dr. Murphy |
| Bí Mật Bên Kia Khung Cửa | Jane Russell 2 | |
| 2020 | Người Sở Hữu | Girder |
| 2019 | QT8: The First Eight | Self |
| Sid & Judy | Judy Garland (voice) | |
| 2018 | Cậu bé buôn thuốc | Alex Snyder |
| Vùng Hủy Diệt | Dr Ventress | |
| 2017 | LBJ | Lady Bird Johnson |
| Good Time | Corey Ellman | |
| Amityville: Quỷ Dữ Thức Tỉnh | Joan Walker | |
| 2016 | Morgan | Dr. Kathy Grieff |
| None of Them Are You: Crafting Anomalisa | Self | |
| 2015 | Anomalisa | Lisa Hesselman (voice) |
| Tám Mối Hận | Daisy Domergue | |
| Welcome to Me | Deb Moseley | |
| Alex of Venice | Maureen | |
| 2014 | Me | Kelly |
| Jake Squared | Sheryl | |
| Hateship Loveship | Chloe | |
| Open | Holly | |
| 2013 | Giết Người Yêu Dấu | Naomi Ginsberg |
| The Spectacular Now | Sara Keely | |
| The Moment | Lee | |
| 2010 | Greenberg | Beth (Beller's Party) |
| 2009 | Der Regisseur Uli Edel - Fakten und Fiktion | Self |
| 2008 | Synecdoche, New York | Maria |
| 2007 | Margot at the Wedding | Pauline |
| 2006 | The Making of 'Last Exit to Brooklyn' | — |
| 2005 | Rag Tale | Mary Josephine 'MJ' Morton |
| Easter Sunday | Mother | |
| Palindromes | 'Mark' Aviva | |
| Ngăn Cản Thần Chết | Dr. Beth Lorenson | |
| 2004 | Gã Thợ Máy | Stevie |
| Childstar | Suzanne | |
| 2003 | Vết Cắt | Pauline |
| Celebrity Naked Ambition | Self (archive footage) | |
| 2002 | Searching for Debra Winger | Self (uncredited) |
| Con Đường Diệt Vong | Annie Sullivan | |
| Hey Arnold! The Movie | Bridget (voice) | |
| Crossed Over | Karla Faye Tucker | |
| 2001 | Người Đàn Ông Vắng Mặt | Female Inmate (voice) (uncredited) |
| The Quickie | Lisa | |
| The Anniversary Party | Sally Nash Therrian | |
| 2000 | Skipped Parts | Lydia Callahan |
| The King Is Alive | Gina | |
| Frame by Frame: The Invisible Art of Production Designer Carol Spier | Self | |
| 1999 | Trò Chơi Quái Ác | Allegra Geller |
| 1998 | Thanks of a Grateful Nation | Teri Small |
| The Love Letter | Lizzie Whitcomb | |
| 1997 | Washington Square | Catherine Sloper |
| A Thousand Acres | Caroline Cook | |
| Cinema Cinema | Herself | |
| 1996 | Bastard Out of Carolina | Anney Boatwright |
| Kansas City | Blondie O'Hara | |
| 1995 | The First 100 Years: A Celebration of American Movies | Self |
| Georgia | Sadie Flood | |
| Dolores Claiborne | Selena St. George | |
| 1994 | Would You Kindly Direct Me to Hell?: The Infamous Dorothy Parker | Self |
| Mrs. Parker and the Vicious Circle | Dorothy Parker | |
| The Hudsucker Proxy | Amy Archer | |
| 1993 | Short Cuts | Lois Kaiser |
| Luck, Trust & Ketchup: Robert Altman in Carver Country | Self | |
| 1992 | Single White Female | Hedra 'Hedy' Carlson |
| The Prom | Lana | |
| 1991 | Rush | Kristen Cates |
| Crooked Hearts | Marriet Hoffman | |
| Bức Tường Lửa | Jennifer Vaitkus | |
| 1990 | Partners in Life | Blossom |
| Buried Alive | Joanna Goodman | |
| Miami Blues | Susie Waggoner | |
| 1989 | The Big Picture | Lydia Johnson |
| Last Exit to Brooklyn | Tralala | |
| 1988 | Heart of Midnight | Carol |
| 1987 | Under Cover | Tanille Laroux |
| Sister, Sister | Lucy Bonnard | |
| 1986 | Picnic | Madge Owens |
| The Men's Club | Teensy | |
| Kẻ Đón Đường | Nash | |
| 1985 | Flesh + Blood | Agnes |
| 1984 | Grandview, U.S.A. | Candy Webster |
| 1983 | Girls of the White Orchid | Carol Heath |
| Easy Money | Allison Capuletti | |
| Have You Ever Been Ashamed of Your Parents? | Andrea Fairchild | |
| 1982 | The First Time | Bonnie Dillon |
| Fast Times at Ridgemont High | Stacy Hamilton | |
| Wrong Is Right | Young Girl | |
| 1981 | The Best Little Girl in the World | Casey Powell |
| The Killing of Randy Webster | Amy Wheeler | |
| I Think I'm Having A Baby | Laurie Mcintyre | |
| Eyes of a Stranger | Tracy Harris | |
| 1980 | Angel City | Kristy Teeter |
| 1978 | The Young Runaways | Heather |
| 1976 | Tod eines Fremden | Girl Playing with Ball (uncredited) |
| 2010 | Greenberg | Story |
| Greenberg | Producer | |
| 2001 | Người Đàn Ông Vắng Mặt | Thanks |
| The Anniversary Party | Director | |
| The Anniversary Party | Writer | |
| The Anniversary Party | Producer | |
| 2000 | 3 Kẻ Trốn Tù | Thanks |
| Skipped Parts | Co-Producer | |
| 1995 | Georgia | Producer |
Theo dữ liệu phòng vé Việt Nam (Box Office Vietnam), Jennifer Jason Leigh có 1 phim với tổng doanh thu 1.78 tỷ.
Phim doanh thu cao nhất là "Tội Phạm 101" (2026) với 1.78 tỷ tại phòng vé Việt Nam.
Jennifer Jason Leigh là diễn viên, sinh tại Hollywood, Los Angeles, California, USA.